Biology Services
Contract research from the drug idea through hit finding and lead optimization
Biology at Enamine is Bienta: a specialized department of Enamine focused on biological testing services, and an independent contract research organization in its own right. It supports early preclinical product development across pharmaceuticals, biotechnology, nutrition, animal health and specialty chemicals, with expert scientists working in high-throughput screening, bioanalytical, mass spectrometry and in vivo groups.
- Screening Compounds
- 4.8M+
- PhD Staff
- 40%
- Customers
- 20 countries
- Coverage
- Idea → PoC
Molecular Screening (HTS)
High-throughput screening against Enamine's own collection or against yours, run in the dedicated HTS laboratory, with hit confirmation and dose-response follow-up.
- Direct access to 4.8M+ in-house screening compounds
- Hit confirmation and dose-response
- Screening by mass spectrometry
ADMET and Pharmacokinetics
- Metabolic stability and clearance
- Permeability and transporter assays
- Plasma protein binding
- CYP inhibition and induction
- Bioanalytics by LC-MS/MS in the bioanalytical laboratory
Animal Studies
Run in the in vivo research facility.
- Formulation screening
- Pharmacokinetics and pharmacodynamics
- Toxicology and dose-range finding
- Pathology models, including cancer research
- Aging studies and behavioural assessment
Recombinant Protein Production
Expression and purification supporting assay development, structural biology and screening campaigns.
In Silico Modelling and Chemoinformatics
Computational support alongside the wet work, and a New Technology Department developing the assays that do not exist yet.
Why Enamine Biology
40% of the biology staff hold PhDs. Chemistry and biology sit under one roof, so hit follow-up, resupply and lead optimization are coordinated rather than handed between vendors.